Avana 100mg Tablet

Description

What is Avana 100mg?

Avana 100mg tablet is used for the treatment of erectile dysfunction (impotence) in men. It works to enhance the penile blood flow by relaxing & increasing the smooth muscles & blood vessels size. It contains Avanafil as an active ingredient used in the treatment of erectile dysfunction.

Avana 100mg (Avanafil) tablet is a phosphodiesterase type 5 inhibitor help men with erectile dysfunction (impotence) to achieve penile erection during intercourse. It works by increasing the vasodilatory impact of cyclic guanosine monophosphate (cGMP) in the penis’ corpus cavernosum. This mechanism facilitates the physiological process of erection upon sexual stimulation by encouraging smooth muscle tissue relaxation and, as a result, increasing blood flow to the penile region.

When compared to other PDE5 inhibitors, Avana 100mg is notable for its quick start of action and comparatively short duration of effect, which makes it a desirable choice for people looking for quick and efficient relief from ED symptoms. To ensure the best possible treatment outcomes and patient satisfaction, healthcare providers must determine whether a patient is a good fit for using Avana 100mg and offer the required counselling.

What are The Uses of Avana 100mg Tablets?

Avana 100mg tablet is used in men who are unable to achieve an erection during intercourse due to sexual function problem [erectile dysfunction (impotence)]. It works to promote the growth of blood flow supply in the male genital area.

• The main indication for using Avana 100mg in adult males is to treat erectile dysfunction (ED).
• It helps create and maintain a satisfying erection by increasing blood flow to the penis during sexual stimulation, hence improving erectile function.
• Designed for people who have trouble getting or maintaining an erection strong enough for sexual activity.
• Effective in a variety of ED etiologies, including organic, psychogenic, and mixed causes, making it a flexible treatment option for men with a range of underlying conditions affecting erectile function. 
• Employed as a pharmacotherapeutic option to address physiological and psychological factors contributing to ED, promoting sexual satisfaction and overall quality of life.

What are The Dosage Guidelines for Avana 100mg Tablets?

• Avana 100 mg tablets should be taken by mouth with water about 15 to 30 minutes before sexual exercise. This is the standard dose. Everyone’s amount should not be higher than one tablet per day, but it can be changed based on how well it works and how well it is tolerated.
• Take Avana 100 mg with or without food, according to the directions on the bottle. You should avoid eating high-fat foods right before taking the medicine, though, for the best results, since this can make it take longer for it to work.

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Missed Dosage Guidelines:

Timing: There is no set dosing plan for Avana 100 mg because it is taken as needed for erectile dysfunction. So, the idea of missing an amount doesn’t make sense. Just take the medicine as directed, about 15 to 30 minutes before getting physical.

Limit on Doses: You should not take more than one 100 mg dose of Avana in a 24-hour time. If you miss or don’t take a dose, you should wait until at least 24 hours have passed since the last dose before taking the medicine again.

Overdosage Guidelines:

Get medical help right away: If you take too much Avana 100 mg, you need to see a doctor right away. Overdosing can have very bad effects, like priapism (a long-lasting erection), severe dizziness, passing out, or other major health problems.

Treatment for Symptoms: Symptomatic and comforting treatment should be used to treat an overdose. Health care workers may keep an eye on a patient’s vital signs and act on certain symptoms as needed to make sure the patient stays safe and recovers.

How does Avana 100mg Tablet Work?

Avana 100mg (Avanafil) is a medication used to treat male erectile dysfunction. It works to achieve an erection during intercourse.

• Avanafil, the active ingredient in Avana 100mg, is a strong and specific inhibitor of phosphodiesterase type 5 (PDE5), an enzyme that is mostly present in the smooth muscle cells of the corpus cavernosum.
• Nitric oxide (NO), which is released during sexual stimulation, promotes the synthesis of cyclic guanosine monophosphate (cGMP) in penile tissue.
• By acting as a second messenger, cGMP promotes penile blood vessel dilatation and smooth muscle cell relaxation, which increase blood flow and cause the penis to enlarge.
• PDE5 causes detumescence by breaking down cGMP, which restricts its function. By inhibiting PDE5 activity, Avana 100mg increases sustained penile erection and prolongs the benefits of cGMP.
• By preventing the breakdown of cGMP, Avana 100mg improves the erectile response to sexual stimulation, resulting in better erectile function and satisfying sexual performance.
• There is a therapeutic window for sexual activity with Avana 100mg because of its quick (15 minutes post-administration) onset of action and prolonged duration of action (4-6 hours).

What are The Side Effects of Avana 100mg Tablets?

Some side effects of vriligy 60mg tablets are given below:

• Nausea
• Headache
• Dizziness
• Dry Mouth
• Fatigue
• Diarrhoea or Constipation
• Insomnia
• Sweating
• Blurred Vision
• Anxiety or Nervousness

Precautions & Warnings:

• Cardiovascular Risk

People who have had a myocardial infarction, stroke, or life-threatening arrhythmias should be very careful when taking Avana 100 mg, because sexual action may exacerbate heart problems. Prior to giving Avana 100mg, doctors should check the patient’s cardiovascular health.

• Hypotension

Avana 100 mg may make the effects of nitrates or alpha-blockers that lower blood pressure stronger. As a precaution, patients should be told not to take Avana 100 mg at the same time as these medicines, and doctors should be careful when prescribing Avana 100 mg to people who are already taking heart drugs.

• Priapism 

Avana 100 mg has been linked to priapism and erections that last longer than 4 hours. Priapism is a rare but serious medical condition that needs quick medical attention to avoid tissue damage and permanent erectile dysfunction. Instruct patients to get emergency medical help if an erection lasts more than 4 hours or hurts.

• Vision Loss

Many people who take PDE5 inhibitors, like Avana 100mg, have reported cases of non-arteritic anterior ischemic optic neuropathy (NAION), a condition that can lead to blurred or lost vision, sometimes permanently. Advise patients to stop taking Avana 100 mg and get medical help right away if they suddenly lose their sight or notice changes in their vision.

• Hepatic Impairment

Patients with weak to moderate hepatic impairment (Child-Pugh Class A or B) should be very careful when taking Avana 100 mg. Drug interactions with avanafil may be different in people whose livers aren’t working properly, so the amount may need to be changed or the patient must be closely watched for any bad effects. Serious liver problems (Child-Pugh Class C) should not take Avana 100 mg.

• Nephrological Problems

People who have mild to moderate renal failure (creatinine clearance 30 to 80 mL/min) should be careful when taking Avana 100 mg. People with kidney problems may need to change their doses or closely watch for side effects because avanafil’s pharmacokinetics may change. Chronic kidney disease (creatinine clearance <30 mL/min) people should not take Avana 100 mg.

When Not to Take Avana 100mg Tablet ?

• Taking Avana 100 mg is not recommended for people who have had a recent myocardial attack (within 90 days), a stroke (within 6 months), unstable angina, or severe heart failure.Since sexual action may increase the risk of heart disease
• Users of Avana 100 mg should not take it if they are also taking nitrate medicines, including Nitroglycerin and Isosorbide dinitrate, because it could cause severe low blood pressure and a higher chance of heart failure.
• Those  who are also taking alpha-blockers, like Doxazosin and tamsulosin, or These actions could cause hypotension with symptoms
• Not recommended for people who are allergic to avanafil or any of the tablet’s ingredients (hypersensitivity). Patients who have allergic responses like rashes, itching, swelling, or trouble breathing should stop taking the medicine and see a doctor.
• Patients with serious hepatic impairment (Child-Pugh Class C) should not take Avana 100 mg.
• Patients with serious renal impairment (creatinine clearance <30 mL/min) should not take Avana 100 mg.

Interaction:

• Not taking Avana 100 mg with nitrate medicines (like nitroglycerin or isosorbide dinitrate) for heart problems like angina is not recommended. When taken together, these things can make your blood pressure drop significantly and potentially dangerously.
• While taking Avana 100 mg, people who are also taking alpha-blockers (such as doxazosin and tamsulosin) may experience symptomatic hypotension. Alpha-blockers should be taken regularly by patients before starting Avana 100mg.
• Antihypertensives: Avana 100 mg may make the blood pressure-lowering effects of hypertension drugs stronger, which raises the risk of unstable angina. Checking blood pressure and changing the amounts of blood pressure medicines may be needed.
• CYP3A4 Inhibitors: Strong inhibitors of the cytochrome P450 3A4 enzyme, such as ketoconazole, ritonavir, and clarithromycin, can raise the amount of avanafil in the blood, which could affect its harmful effects more. Changing the dose of Avana 100 mg might be needed.
• While taking Avana 100 mg, CYP3A4 inducers like rifampin and phenobarbital can lower their effectiveness by lowering their levels in the blood. For some people, higher amounts of Avana 100 mg may be needed to get the intended result.
• Additionally, taking Avana 100 mg at the same time as other PDE5 inhibitors (like sildenafil or tadalafil) is not suggested because of the higher chance of side effects like low blood pressure and priapism.

FAQs:

1) What is Avana 100mg?

Ans: Avana 100mg is a medication used to treat erectile dysfunction (ED) in adult men.

2) How long does Avana 100mg last?

Ans: The effects of Avana 100mg typically last for about 4-6 hours after ingestion.

3) Can Avana 100mg be taken by individuals with Peyronie’s disease?

Avana 100mg should be used with caution in individuals with Peyronie’s disease, as it may exacerbate penile curvature.

4) Can Avana 100mg be taken by individuals with penile implants?

Ans: Avana 100mg should be used with caution in individuals with penile implants, as it may interfere with the function of the implant.

5) Can Avana 100mg be taken by individuals with glaucoma?

Ans: Avana 100mg should be used with caution in individuals with glaucoma, as it may increase intraocular pressure.